http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4230923-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b172e4dc6f8b115773eb99a04e8260f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 |
| filingDate | 1992-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d5ef58b717314578ff0810835744c89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59ac28ebcd82e3636efc64c5f9c0d969 |
| publicationDate | 1993-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4230923-A1 |
| titleOfInvention | Process for the preparation of 2-mercaptobenzimidazoles, oxazoles and thiazoles |
| abstract | Prodn. of 2-mercapto-benzimidazoles, -benzoxazoles and -benzothiazoles of formula (I) is effected by reacting an aniline deriv. of formula (II) with CH2Cl2 and S in an inert solvent in the presence of an acid binder (III). X=O, S or NH; R=H, 1-3C alkyl, 1-3C alkoxy, CF3 or halogen. The reaction is effected at reflux temp. using 1 mole CH2Cl2, 2 moles S and 2 moles (III) per mole (II). The solvent is an alcohol or aromatic hydrocarbon. (III) is a tert. amine, esp. NEt3 or pyridine. USE/ADVANTAGE - (I) are useful as pharmaceutical intermediates. The process gives high yields (e.g. 80-97%) without using highly toxic reagents such as CSCl2 or CS2. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9746544-A1 |
| priorityDate | 1992-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.