http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4220369-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8dbdfc93841b3d731fbab7ea48b412a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 1992-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3fecd70a170aa52dc92ddef38679ec0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1afe184f674c3c78ba7299893b651861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9210f26d29999096078da0990cf0ae3a |
| publicationDate | 1993-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4220369-A1 |
| titleOfInvention | Novel fused dihydropyridine acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them (C.V.) |
| abstract | Fused-ring dihydropyridine acetic acid derivs. of formula (I) and their acid-addn. salts are new. A = benzo, thieno or indolo (also pyrrolo in disclosure); when A = benzo, m = 2 and R11 = OH, 1-4C alkoxy, mesyloxy or NHSO2Me, or adjacent R11+R11 = OCH2O or OCH2CH2O (M and R11 are not otherwise defined); R1 = 4-6C cycloalkyl or (4-6C)cycloalkyl(1-5C)alkyl, or when A = pyrrolo, R1 may also be H, 1-10C alkyl, phenyl(1-5C)alkyl, 1-4C alkoxy or NHCOX (X - 1-5C alkyl); R2 and R3 = H or 1-5C alkyl, or CR2R3 is a 5- or 6-membered carbocyclic ring; R5 = H or 1-4C alkyl; R4 = 1-4C alkoxy or NR9R10; R9 and R10 = H, 3-6C alkenyl, 3-6C alkynyl, or 1-12C alkyl opt. substd. by OH, 1-4C alkoxy, di(1-4C alkyl)amino, furyl, pyridyl, pyrrolidinyl, morpholino, indolyl, CN, thienyl or phenyl (opt. substd. by OH, OMe, F, NHSO2Me, mesyloxy or OCH2O); or R9 = H and R10 = phenyl, fluorophenyl, pyridyl or N-benzylpiperidyl; or NR9R10 = pyrrolidino, piperidino, morpholino or 1-piperazinyl opt. 4-substd. by Me, Ph, mono- or di(1-4C alkoxy)phenyl, pyrimidinyl or phenyl(1-4C)alkyl. USE/ADVANTAGE - (I) are cardioprotective and cerebroprotective agents, antiinflammatory agents (e.g. for treating asthma and arthritis), and anticoagulants or platelet aggregation inhibitors. |
| priorityDate | 1992-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.