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filingDate 1992-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-4208258-B4
titleOfInvention Process for the preparation of crystalline ciclosporin in spherical particle form and its use, in particular for pulmonary administration
abstract methodnfor the preparation of crystalline cyclosporin in spherical particle formnwith an average diameter of less than 50 μm, comprising:nConversion of crystalline cyclosporin in non-spherical particle formnat a temperature of about 20 to 60 ° C below the melting pointnThe crystalline modification that is converted is atnTo pressnfrom 101 to 253 kPa and overna period of 1 to 5 minutes in dispenser phase.
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