| abstract |
Diaminoacid amides of formula R2NH-CH((CH2)nNHR1)-CONR3R4 (I) and their salts, are new. n = 2-4; R1, R2 = H or acyl; and R3, R4 = alkyl or aralkyl; or NR3R4 = a heterocyclic ring (opt. substd.). Pref. R1, R2 = Ac, propionyl, or t-pentanoyl, pref. R1 = Ac, R2 = H; NR3R4 = a 5 or 6 membered heterocyclic ring (opt. substd. by COOH, and opt. contg. other heteroatoms, esp. O and S); or R3, R4 = 1-10C alkyl or aralkyl. |