abstract |
2-Amino-3-cyano-pyridine derivs. of formula (I) are new: In (I) R1 = H, 1-4C alkyl, mono- or polycycloalkyl, cycloalkenyl, phenylalkyl, alkoxyphenylalkyl, aryl, halophenyl, alkylphenyl, trifluoromethylphenyl, cycloalkyl-phenyl, a heterocyclic residue (contg. O or S as ring atom) or phenyl substd. by a heterocyclic substit. (contg. N and opt. O); R2 = H, 1-4C alkyl, phenylalkyl or aryl; R3 = H, 1-4C alkyl or aryl; or R1+R2 or R2+R3 = (CH2)n (opt. substd. by 1-4C alkyl, phenyl or a ketal gp) or a benzofused alkylene bridge of formula (i): n = 3,4,5,6,10 or 13; m = 1,2 or 3. USE - (I) are selective inhibitors of human cytomegalovirus. |