http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-4101394-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fa05d3fae8bd51fd561f4064e80b510 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate | 1991-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86aa77d0c5612a87c6ad923f03daa4d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67f23146633379692420e2bdce7bfb55 |
| publicationDate | 1992-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-4101394-A1 |
| titleOfInvention | METHOD FOR COUPLING CARBOHYDRATES TO CARRIERS, IN PARTICULAR PROTEINS |
| abstract | A process is prepared for coupling carbohydrates or compounds containing a carbohydrate unit to substrates, especially proteins. In this process, use is made in the first stage of a carbohydrate having a free or hemiacetally bonded aldehyde group, or a compound whose carbohydrate unit has such an aldehyde group. This aldehyde group is reductively aminated. Via the amino group thus introduced into the carbohydrate or carbohydrate unit, an organic coupling component bearing a thiol group is bonded so as to form a carbohydrate-coupling component conjugate. The carbohydrate-coupling component conjugate thus formed is coupled in a second stage via the thiol group to a couplable substrate so that the conjugate is covalently bonded to the substrate via a disulphide group or a thioether bridge. The modified substrates of the invention to which a carbohydrate is coupled can be used for immunological purposes, in biochemical analysis and in patho-biochemistry. |
| priorityDate | 1991-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.