abstract |
Substd. 1,2,4-triazinediones (I) are new, where X= O or S; Y= O, S, CO, CH(OH) or C(CN)(R3); R1= 1-4C haloalkyl; R2= H, halogen or 1-4C haloalkyl; R3= H or 1-4C alkyl; R4= H, halogen, haloalkyl or 1-4C alkyl; R5= H, 1-4C alkyl, haloalkyl, aralkyl or alkynyl. Intermediates (III), (IV) and (V) are also claimed, where A= COOH in cpds. (III); and R7 in cpds. (IV). R7= CN or -CON(R5)COOR8; R8= alkyl or aryl. USE - (I) are used for the control of parasitic protozoa and fish parasites. They are esp. effective against coccidiosis in poultry, where they are given in the feed in amts. of 0.5-100 ppm, and in mammals, where the dosage is e.g. 0.5-100 mg/kg. |