http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3919246-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8dbdfc93841b3d731fbab7ea48b412a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147 |
| filingDate | 1989-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9210f26d29999096078da0990cf0ae3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe1f3a75826fc334ab86ae60be7d49f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3fecd70a170aa52dc92ddef38679ec0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1afe184f674c3c78ba7299893b651861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc97ed6ba8240d0c95e358fe31c6ff25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_960d2b0f2e0a0b30a47a1c1e2a8317c5 |
| publicationDate | 1990-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-3919246-A1 |
| titleOfInvention | ANELLELED TETRAHYDROINDOLICINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| abstract | New derivatives are of general formula (I). A = H, CH3, CH20H, 1-5C alkyl-0CH2, 1-4C alkyl-0C0CH2, CH2NH2, 1-5C alkyl-0C(R)NCH2 or CH2NHR; R, R3, R4 = H; or (un)substitd (2-12C)1-12C branched or linear hydrocarbon (II) 3-6C cyclic hydrocarbon; or unsubsttd or up to 5 times substd phenyl, where (II) can be substd once or pref twice -0H, 0CH3, -NH2, 1-5C alkyl-NH2, di-(1-5C alkyl-NH2), 3-6C cycloalkyl, phenyl or 5-6 membered unsubstd heterocycle. B = (i)-(v); X = S or NH, NCH3, N-Bensyl; Y = S, 0 or NH, NCH3, N-Benzyl; R1, R2 = H, 1-4C alkoxy, mercapto, methylmercapto, amino, or 0-(CH2)n-0; n = 1-2; R8 = H, 1-3C alkyl, 3-6C cycloalkyl or -SCH3; or opt R3 and R4 can form a 5-6 membered ring with N, in which this ring opt contains N, 0 or S. (I) can either be administered enterally or parenterally in an amt of 2-20 mg/kg, pref 5-10 mg/kg 1-3 times a day. USE/ADVANTAGE - (I) is useful in pharmaceutical prepns exhibiting a cardio-protective effect |
| priorityDate | 1989-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.