http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3917287-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-06 |
| filingDate | 1989-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd60edb4f2b97add6e4e8e4f8a74ead2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feb01cfe71f9a94f250df73c681d9af3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9c90541b91feacf0945cd5a6404c4f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b794e0c2f00d1da31bfd5bfdc0c36541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_942ff7de4542f7284ec6c22c116387f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d595dbdd39c4b061ae56d22b8245cd02 |
| publicationDate | 1990-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-3917287-A1 |
| titleOfInvention | METHOD FOR PRODUCING PENEM COMPOUNDS |
| abstract | Prodn. of penem cpds. of formula (I) is effected by reacting a 4-acylthio-1-oxalyl-2-azetidinone of formula (II) with a phosphonite diester of formula (III). R1 = H, 1-4C alkyl, 1-12C alkoxy, 1-12C alkylthio, OAr, Ar, 3-6C cycloalkyl, 3-6C cycloalkyloxy, 5-6C oxacycloalkyl (opt. mono- or diunsatd.), 3-6C oxocycloalkyl, gem-di(1-3C)alkoxy(3-6C)cycloalkyl, (1-3C)alkylimino(3-6C)cycloalkyl, arylimino(3-6C)cycloalkyl, hydroxyimino(3-6C)cycloalkyl or (1-3C) alkoxyimino(3-6C)cycloalkyl, where the cycloalkyl gps. are opt. mono- or diunsatd. and opt. mono- or disubstd. by 1-3C alkyl, 1-3C alkoxy, halogen or methylene; Ar = phenyl opt. substd. by 1 or 2 of COOH, 2-5C alkoxycarbonyl, allyloxycarbonyl, CONH2, 1-4C alkylcarbamoyl, CN, F, Cl and/or Br; R2 = H or a protecting gp. removable by hydrolysis, photolysis, oxidn., redn. or enzyme treatment; R3 = H, 1-4C alkyl, 2-4C alkenyl, 1-4C alkoxy, 4-7C cycloalkyl, phenyl, 2-oxo-1,3-dioxolyl, triazolyl, thiazolyl, NH2 or acylamino (N.B., in all exemplified cpds., R3 is O-protected 1-hydroxyethyl); R6 = 1-4C alkyl or phenyl opt. substd. by 1-3C alkyl or 1-3C alkoxy; R4 and R5 = 1-4C alkyl, allyl, benzyl or phenyl opt. substd. by 1-3C alkyl or 1-3C alkoxy. |
| priorityDate | 1989-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.