http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3682891-D1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d83198bc2e3204742b5c564869d7b458 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6459 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| filingDate | 1986-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e18d261dbb7ce4e495d81a3d33534785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25d39cff1785de0f52ae507be3b9e943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1456082de96d19c61173dd8f6ddb5a5 |
| publicationDate | 1992-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-3682891-D1 |
| titleOfInvention | TISSUE PLASMINOGEN ACTIVATOR MUTANT, THEREFORE ENCODING RECOMBINANT GENETIC INFORMATION AND METHOD FOR THE PRODUCTION OF THESE MUTANTS, THEIR USE AND PHARMACEUTICAL COMPOSITIONS. |
| abstract | Tissue-type-plasminogen activator (t-PA) mutants comprising at least one kringle domain K2 and/or at least one finger domain (F), including modified forms, having equiv. or improved binding strength and/or binding selectivity towards fibrin, are new. They either lack part of the natural molecule or contain at least 2 K2 and/or F domains. Recombinant genetic information in the form of DNA, single-strand DNA or double-strand DNA coding for t-PA mutants as defined above, is new. Recombinant cloning and/or expression vector, esp. a plasmid, comprising a cloning and/or expression vehicle having the recombinant genetic information defined above inserted in it is new. Micro-organism or cell culture transformed by a vector as defined above is new. |
| priorityDate | 1986-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.