Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2e0a0402ce4ceb945cc040a1c1aa247 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
filingDate |
1985-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28d32d355098e243a0a45b245ce0ea22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce5511e636cc1534692fca074ad0d343 |
publicationDate |
1986-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-3515529-A1 |
titleOfInvention |
METHOD FOR THE SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDES DEFINED SEQUENCE |
abstract |
Essential for the process according to the invention is the use of the 4-carboxyphenoxyacetyl group as spacer group. This makes it possible for the oligonucleotides which have been synthesised on solid phases by processes known per se to be cleaved off the solid phase in such a way that the cleaved-off oligonucleotides have all the required protective groups and, at the same time, also a terminal hydroxyl group. The cleaved-off oligonucleotides are particularly suitable as precursors of oligonucleotides by the known phosphoramidite process. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0215942-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0452420-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0215942-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0452420-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5478893-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5663242-A |
priorityDate |
1985-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |