abstract |
The invention relates to 9-aminoalkyl-8-hydroxyadenines of the general formula I <IMAGE> in which R<1> and R<3> are hydrogen, C1-4-alkyl or C1-4-hydroxyalkyl, R<2> is hydrogen or hydroxyl, A is H or CO(CH2)6R<4> where R<4> is a radical of a macromolecular carrier and n is 0 or 1, to processes for the preparation of these compounds and, if appropriate, their derivatives, and to their use as ligands in the preparation of modified polymeric affinity sorbents for the affinity chromatography of S-adenosyl-L-homocysteine hydrolases. |