http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3322643-C2
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72 |
filingDate | 1983-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1986-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1986-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-3322643-C2 |
titleOfInvention | Process for the production of a latex test reagent for the detection and differentiation of human hemoglobin, human hemoglobin components or human hemoglobin variants |
abstract | The invention relates to a method for producing a latex test reagent from anti-human hemoglobin antibodies or from anti-human hemoglobin constituent antibodies, which is characterized in that 1. from liquids containing these antibodies or fragments of these antibodies, these are precipitated with ammonium sulfate and centrifuged off, 2. the centrifuged solids, after resuspension in a second aqueous medium, dialyzed in this until it is free of sulfate, 3. the dialyzed antibody (or antibody fragment) fraction mixed with an aqueous suspension of polystyrene latex particles and 4. preferably with a temperature of 0 ° C to 100 ° C and 5. then the mixture with a surface-active agent of the general formula $ F1 wherein R is an aliphatic hydrocarbon radical with about 8 to 22 carbon atoms and a, b and c each have a positive Denote a number, the sum of a, b and c preferably being 5 to 200 t, and optionally polyvinylpyrrolidone. The invention also relates to the use of a latex test reagent produced in this way for the detection and differentiation of human hemoglobin, human hemoglobin components or human hemoglobin variants. |
priorityDate | 1983-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.