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filingDate 1982-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1984-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-3224641-A1
titleOfInvention METHOD FOR DETERMINING GLOMERULAR FILTRATION RATES
abstract The invention deals with a method for the determination of the glomerular filtration rate after a single injection of a test dose of a corrinoid and with a method for the determination of tiny amounts of vitamin B12. This may be of importance, for example, in a wide variety of disciplines. An example of this from medicine. Clearance investigations for clinical testing of kidney function are known. Radioactive isotopes are used for this, thus exposing the human body to radioactivity. If it is possible to obtain at least equally good results in clearance investigations without exposing the human body to radioactive isotopes, this would be a great success. This is possible by detection of tiny amounts of vitamin B12 in the human body. This is achieved by saturating the B12 receptors, administering at least one test dose of vitamin B12, and subsequently determining the plasma concentration by HPLC (High Pressure Liquid Chromatography). <IMAGE>
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priorityDate 1982-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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