http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3216300-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D457-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-06 |
filingDate | 1982-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0013552a1230a8354222007a67a7f65a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1245fe96c2c605ca7251f37561357f4 |
publicationDate | 1983-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-3216300-A1 |
titleOfInvention | NEW ERGOTANILIDES, THEIR PRODUCTION AND USE |
abstract | Novel ergot derivatives and a novel process for the preparation of ergot anilides of the general formula <IMAGE> in which C9....C10 denotes a CC single or a C=C double bond, R<2> denotes hydrogen, chlorine or bromine, R<6> denotes C1-4-alkyl and X denotes H, C1-4-alkyl, C1-4-alkoxy, fluorine, chlorine, bromine, NH2, NHR' (R' = C1-4-alkyl and -acyl), NR'R" (R<'> = C1-4-alkyl and C1-4-acyl; R" = C1-4-alkyl and R' and R" together denote a 5- or 6-membered saturated or unsaturated heterocyclic ring, in which a CH2 or CH group can be substituted by N, O or S), and SR"' (R"' = C1-4-alkyl and phenyl), by reaction of appropriate lysergic acid methyl or lysergic acid ethyl esters with a dimethylaluminium anilide in an inert solvent are described. The compounds which can be prepared according to the process are in some cases useful pharmacologically active compounds which are distinguished, in particular, by an antihypotensive activity. |
priorityDate | 1982-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.