abstract |
Novel pyrimidinones of the general formula <IMAGE> in which A and B, together with the two carbon atoms lying in between, form a pyridine or methoxyphenyl ring, D denotes an alkylene or hydroxyalkylene group, R3 and R6 each denote a hydrogen atom or an alkyl group, R4 denotes a hydrogen atom or an alkoxy group and R7 denotes an alkyl group, or an alkylene or hydroxyalkylene group which is terminally substituted by an optionally substituted phenyl group, and their salts, which have useful pharmacological properties, in particular a hypotensive, antiarrhythmic and beta -receptor-blocking action. The compounds of the formula I can be prepared by processes customary for analogous compounds. |