http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3046839-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 |
| filingDate | 1980-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_952591497f1e8246c0190427dd15bebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26d7cf5e3c70bfb405c48bbae5678fe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90cb66493d69fbe8cd7077a72c23de52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dbacd7dfe98da8e87f75fcfbd081425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a4a7bdf6107f676c833f83e6335742f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21e81ee5bd6f41a3ba1a906c3ea7a076 |
| publicationDate | 1982-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-3046839-A1 |
| titleOfInvention | NEW PENICILLINES, THEIR SALTS, PROCESS FOR PRODUCING THESE COMPOUNDS |
| abstract | Penicillins of formula (I) including keto tautomers and their salts with bases are new. In (I) A is phenyl (opt. substd. by 4-hydroxy or 3,4-dihydroxy) or 2-thienyl. R is a gp. of formula (A), Q is -SO2.N:CR1R2, -Y.Z.X or (B). R1 and R2 are each methylthio or amino, and when one is amino, tautomeric forms are included. Z' is O, S or :NRz. Rz and R3 are H or 1-3C opt. hydroxy-substd. alkyl. R4 is H, hydroxy, hydroxymethyl or methyl. n is 2-4; when R3 and/or Rz is H, tautomeric forms are included. Y is SO2NH, SO or SO2. Z is 1-3C alkylene. X is hydroxy, aminocarbonyl, aminosulphonyl, formylamino, acetylamino, amino, methylsulphinyl, methylsulphonyl ot -CH(NH2).COOH. (I) are broad-spectrum antibiotics effective against Gram negative and positive species and can be used in human or veterinary medicine for treating or preventing systemic infections. They are also useful as preservatives for polymers, lubricants, dyes, leather, etc. All (I) tested had oral LD50 over 4g. per kg. and subcutaneous LD50 over 2g. per kg. in mice. Usual daily doses are 10-200mg. per day. |
| priorityDate | 1980-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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