Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-465 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 |
filingDate |
1980-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d29072f407aaf3b1585ac5dc63af7bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc0f7fb9350e3a4704c3356bd19b6ee3 |
publicationDate |
1982-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-3038130-A1 |
titleOfInvention |
(ALPHA) AMYLASINE ACTIVATORS AND METHOD FOR THE PRODUCTION THEREOF |
abstract |
The alpha-amylase inactivators HOE 467-A and HOE 467-B, and their mixts. are new. The amino acid compsn. of HOE 467-A is Asp 6; Thr 8; Ser 5; Glu 7; Pro 3; Gly 7; Ala 7; Val 8; Cys 4; Ile 2; Leu 4; Tyr 6; His 2; Lys 1; Arg 3; Tp 1, and its isoelectric point is 4.38-4.68. The inactivators are prepd. by cultivating Streptomyces tendae ATCC 31210 or HAG 1266 (the second claimed as a new organism) and recovery by adsorption on resins or by reverse-phase chromatography. The inactivators are used to regulate the level of sugars in the blood, esp. for treating diabetes, pre-diabetic states or adiposity. They are resistant to enzymatic degradation; produced no toxic signs in mice when given at 1 g per kg (intraveneously) and are pref. administered at doses of 10000-300000 amylose-inhibiting units. |
priorityDate |
1980-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |