Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-26 |
filingDate |
1980-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7863fc6db34da8c9bff1bbb7b0b8d2d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09ed5f9b6d78f2cb3c11ce10dab2664c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da13107088cbc39bac918f8a345dadc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f59ebba1ec3ddc1976f8905c3b0d006b |
publicationDate |
1982-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-3032709-A1 |
titleOfInvention |
AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF |
abstract |
N-(Aminoacyl)-indoline-or -tetrahydro-isoquinoline-carboxylic acids (I) and their salts are new. n is 0 or 1; A is a fused on benzene or cyclohexane ring; R1 and R2 (both of which are opt. substd.) are 1-6C alkyl or alkenyl, 5-7C cycloalkyl or cycloalkenyl, 7-12C cycloalkyalkyl, 6-10C aryl or partially hydrogenated aryl, 7-14C aralkyl, or a mono-or bicyclic heterocycle with 5-7 or 8-10 ring members of which 1 or 2 may be S and/or O and/or up to 4 may be N; and R3 is H, 1-6C alkyl, 2-6C alkenyl or 7-14C aralkyl. The new cpds. have long-lasting intensive hypotensive activity and can be used for treating hypertenorin due to various causes. Dosages are 20-200 mg. orally or 0.01-10 mg. i.v. or s.c. for admin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4511504-A |
priorityDate |
1980-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |