http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3028239-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60f7db8bbbcce9810801e2e6b41f3a70 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-08 |
filingDate | 1980-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_099e6ce8045b6db4cb2f6513907a2bad |
publicationDate | 1982-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-3028239-A1 |
titleOfInvention | SIMPLE METHOD FOR PRODUCING THEOPHYLLIN-7-BUTTERIC ACID |
abstract | In a new process for the prodn. of theophylline-7-butyric acid (I), theophylline-sodium (II) is reacted with gamma-butyrolactone (III) at elevated temperature, pref. at 150-170 deg.C. Theophylline-7-butyric acid is a medicament with improved absorption. In the form of its conjugate with bovine serum, it is also useful for the immunisation of rabbits. The process is economical (gamma-butyrolactone price 20 DM/kg compared with ca 400 DM/kg for ethyl 4-bromobutyrate), and the reaction proceeds smoothly. The use of expensive solvents is avoided, and the process does not give rise to pollution. |
priorityDate | 1980-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.