| abstract |
8-Diethylureido-6-R-ergoline I derivs. and their 9,10-didehydro analogues of formula (II) and their salts are new: (R is 2-6C alkyl, or a R'-methyl or 2-R'-ethyl gp., where R' is vinyl, ethynyl, 2-7C alkoxycarbonyl or CN, or R is cyclopropyl, cyclobutyl, cyclopropylmethyl or cyclobutylmethyl).. (II) have higher dopaminergic activity than lisuride and can be used for inhibiting lactation and treating Parkinson's disease. |