http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2944222-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-04 |
| filingDate | 1979-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2709cc7b2f81820de23e471fb2a9c4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89688b3afe08b419c23de8f5e90ac99a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c01508d6dbabb74e11876c5de3baee5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63d6e41574b6b03f3da8551cf919c301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_303f21d96f69c4c02c2748a25ab241cd |
| publicationDate | 1981-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2944222-A1 |
| titleOfInvention | NEW AMINO DERIVATIVES OF 1,2-BENZISOTHIAZOLE |
| abstract | Novel amino-derivs. of 1,2-benzisothiazole are of formula (I). n is 2 or 3; R1 and R2 are H or opt. branched 1-5C alkyl; R3 is Ph, opt. mono-, di- or tri-substd. by halogen, alkyl, alkoxy, alkylthio, haloalkyl or haloalkoxy (these 2 gps. contg. 1-3 halogen), hydroxyalkyl or alkoxyalkyl (all alkyl gps. contg. 1-5C), 2-6C alkenyl, alkinyl or alkinyloxy, 3-8 ring C cycloalkoxy, methylene dioxy, amino, 1-5C alkylamino or di(1-5C)alkylamino. R3 may also be indanyl or tetrabydropaphthyl). The physiologically acceptable acid addn.-salts of (I) are also new. (I) are pharmaceuticals and can be used in heart and circulatory disorders. As a result of their beta-sympatholytic action, (I) are esp. suitable for the treatment of coronary heart disease, hypertonia and disturbances of cardiac rhythm. Suitable unit doese for humans are 1-100 (sp. 3-50) mg. (I) are strong beta-sympatholytics of low toxicity and have a therapeutic breadth 3-12 times greater than that of the known beta-sympatholitic propandol. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6521667-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7202261-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6022894-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6432656-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6818660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9737967-A1 |
| priorityDate | 1979-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.