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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
filingDate 1979-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64affa9e1030985af230c7724b4e7134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b9470976cf64d3c0c45909cfdd191b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f33554e9eb94e0b60d6badd636eb73
publicationDate 1981-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-2929972-A1
titleOfInvention METHOD FOR PERMANENTLY PRODUCING MONOCLONAL IMMUMGLOBULINE ANTIBODIES OF THE MOUSE WITH KNOWN HAPTEN SPECIFICITY
abstract Prodn. of a mouse immunoglobulin E (IgE) antibodies, where IgE-antibody-producing hybrid cell lines with known hapten specificity are prepd., and after growth the IgE- antibodies are isolated, is claimed. The hapten-specific IgE antibodies are capable of inducing specific and reproducible local and systemic allergic reactions in experimental animals. IgE-anti-DNP-antibodies produced by the new process are partic. suitable for the testing of antiallergic cpds; they can also be used to give animal models of food allergies and percutaneously induced allergies. The antibodies are monoclonal and therefore give qualitatively and quantitatively reproducible results. Unlike IgE-contg. immune-sera, the prods. are free from other classes of immunoglobulin (e.g. IgG (1)) with the same hapten specificity and from IgE antibodies of unknown allergen specificity.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3628956-A1
priorityDate 1979-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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