http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2929972-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate | 1979-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64affa9e1030985af230c7724b4e7134 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b9470976cf64d3c0c45909cfdd191b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f33554e9eb94e0b60d6badd636eb73 |
publicationDate | 1981-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-2929972-A1 |
titleOfInvention | METHOD FOR PERMANENTLY PRODUCING MONOCLONAL IMMUMGLOBULINE ANTIBODIES OF THE MOUSE WITH KNOWN HAPTEN SPECIFICITY |
abstract | Prodn. of a mouse immunoglobulin E (IgE) antibodies, where IgE-antibody-producing hybrid cell lines with known hapten specificity are prepd., and after growth the IgE- antibodies are isolated, is claimed. The hapten-specific IgE antibodies are capable of inducing specific and reproducible local and systemic allergic reactions in experimental animals. IgE-anti-DNP-antibodies produced by the new process are partic. suitable for the testing of antiallergic cpds; they can also be used to give animal models of food allergies and percutaneously induced allergies. The antibodies are monoclonal and therefore give qualitatively and quantitatively reproducible results. Unlike IgE-contg. immune-sera, the prods. are free from other classes of immunoglobulin (e.g. IgG (1)) with the same hapten specificity and from IgE antibodies of unknown allergen specificity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3628956-A1 |
priorityDate | 1979-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.