http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2912032-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-17 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 |
| filingDate | 1979-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d12c0baee4b9995db62ce4fd076a5d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af16b0fbcc0c1261e2b28a9f7771c69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad4a69b7f86f3993d508241cd1ddde2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_802a2165763d631e5cb74e8612ee59c3 |
| publicationDate | 1980-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2912032-A1 |
| titleOfInvention | ANILINOTROPONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM |
| abstract | New anilinotropone derivs. are of formual (I) (where R is H or Me). (I) are prepd. by reacting a tropone cpd. (III); X is F, Cl, Br, tosyloxy or methoxy) with an aniline deriv. (III; Y is carboxyl, ester or nitrile) and (when Y is not carboxyl) subjecting the resulting intermediate to hydrolysis. In the reaction, an acid scavenger such as potassium carbonate, sodium acetate or triethylamine may be used. In addn., the reaction may be promoted by an iodide, such as sodium or potassium iodide, and Ullmann catalyt, such as active copper or copper sulphate. The reaction solvent is e.g. benzene, ethanol, t-butanol, tetrahydrofuran, acetone, dimethylsulphoxide or dimethylformamide. The reaction is at from room temp. to reflux temp., while monitoring the reaction mixt. by spectrometry observing the absorption bands around 345 nm and 405 nm which are characteristic to the anilinotropone structure. |
| priorityDate | 1979-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.