http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2910992-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78c33487d6b93e634f5a0e62cf4dcdbf |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1013 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103 |
| filingDate | 1979-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374d685c0f47f13ecf84efe8214154b0 |
| publicationDate | 1980-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2910992-A1 |
| titleOfInvention | METHOD FOR PRODUCING L-THREONYL-L-LYSYL-L-PROLYL-L-ARGININE |
| abstract | Prepn. of L-threonyl-L-lysyl-L-prolyl-L-arginine (I) is carried out by (a) reacting N-benzyloxycarbonyl-L-threonine (II) with Epsilon -benzyloxycarbonyl-L-lysin methyl ester (III) by the carbodiimide method to form N-benzyloxycarbonyl-L-threonyl -(Epsilon-benzyloxycarbonyl)-L-lysine methyl ester (IVa); (b) hydrolysing (IVa) to form N-benzyloxycarbonyl-L-threonyl-(Epsilon-benzyloxycarbonyl)-L-lys- ine (IVb); (c) converting (IVb) to N-benzyloxycarbonyl-L-threonyl-(Epsilon-benzyloxycarbonyl)-L-lys- yl-L-proline methyl ester (Va) by the carbodiimide method; (d) hydrolysing (Va) to form N-benzyloxycarbonyl-L-threonyl-(Epsilon-benzyloxycarbonyl)-L-lys- yl-L-proline (Vb); (e) converting (Vb) to N-benzyloxycarbonyl-L-threonyl-(Epsilon-benzyloxycarbonyl)-L-lys- yl-L-prolyl-(Nomega-nitro)arginine methyl ester (VIa) by the carbodiimide method; (f) hydrolysing (VIa) to form N-benzyloxycarbonyl-L-threonyl-(Epsilon-benzyloxycarbonyl)-L-lys- yl-L-prolyl-nitroarginine (VIb); and (g) hydrogenating (VIb) to form (I). (I) is a peptide hormone (tuftsin) occuring in leucophilic gamma-globulin fractions. |
| priorityDate | 1979-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.