http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2906239-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e987ddd7d0967e4278a229b67adf8809 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 |
filingDate | 1979-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ea82583370275d77e86d46fd23f51dc |
publicationDate | 1980-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-2906239-A1 |
titleOfInvention | RIGHT-ROTATING (+) - ENANTIOMERES AND LEFT-ROTATING (-) - ENANTIOMERES OF BETA -DIMETHYL-AMINO-AETHYL- (PHENYL-METHYL-2-PYRIDYL) -CARBINOLAETHERS |
abstract | New cpds. are (+) - and (-)-enantiomers of 2-dimethylamino-ethyl phenyl-methyl-(2-pyridyl)-carbinol ether (doxylamine) (I), and their salts with organic carboxylic acids (esp dicarboxylic acids). In the guinea-pig isolated ileum prepn, (+)-(I) has more antihistaminic action at a lower concs than (-) - (I). (+)- (I) prolongs hexobarbital sleeping time in guinea pigs, while (-)-(I) greatly reduces this (+)-(i) is useful as an anthihistamine and/or as a sedative and hypnotic agent, while (-)-(I) is useful as an anthihistaminc for daytime use. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103467365-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107098851-A |
priorityDate | 1979-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.