http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2844596-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-937 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-937 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
| filingDate | 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf343c7651fa9f47d50728df99f05c46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0443ecd21ed1c62553680d976135245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b43e86a9d6eb008954fcf80af5d2261f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2b2e4b12a026de710d679f5b32c1ab6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93ef6d0b4959f5407f04dc03e874b388 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_834881e4b181a49bdc251d3fc68339d4 |
| publicationDate | 1980-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2844596-A1 |
| titleOfInvention | NEW PROSTACYCLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS |
| abstract | Prostacyclin derivs. of formula (I) and their salts are new. In (I), R1 is H or opt. substd. alkyl; R2 is H or alkyl; R3 and R4 are H or opt. substd. alkyl or aralkyl, provided that one is H when the other is aralkyl; n = 0-2; m = 0-8; A is CN, alkoxycarbonyl, aralkoxycarbonyl, N,N-disubstd. carbamoyl or bicycloalkenyl. Specified activities of (I) are (i) inhibition of blood platelet aggregation, (ii) inhibition of thromboxaneA2 synthesis and antagonism of thromboxaneA2 action, (iii) inhibition of gastric secretion, and (iv) suppression of undesirable gastrointestinal effects due to administration of prostaglandin synthetase inhibitors. Specified uses include treatment of thrombosis, cerebral ischaemic attacks, ulcers, vascular disorders, etc., control of oestrus, and induction of abortion. Cpds. (I) have a narrower activity spectrum than natural prostacyclin, with fewer side effects and a longer-lasting action. |
| priorityDate | 1978-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.