http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2811132-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44e0905262f429c7590b40df8448c0c5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate | 1978-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee8c95f31bb81a26a44264b5b1fb7954 |
| publicationDate | 1979-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2811132-A1 |
| titleOfInvention | NEW DERIVATIVES OF 1-HYDROXY-BENZO-2,3,1-DIAZABORINE, MEDICINAL PRODUCTS CONTAINING THESE AND PROCESS FOR THE PREPARATION |
| abstract | Benzodiazaborine derivs. of formula (I) are new: In (I), R1 is an alkyl gp. opt. substd. by 1-3 halogen, pref. Cl atoms, or a 2-5C alkenyl gp., R2 and R3 are 1-4C alkyl, F, Cl or Br, or one of R2 and R3 can be H; R4 is H or a cation, pref. alkali metal. Specific (I) are 1-Hydroxy-2-(3-chloropropylsulphonyl)-6-methyl-benzo-2,3,1-diazab- orine, 1-hydroxy-2-(isobutyl-sulphonyl)-6-methyl-benzo-2,3,1-diazaborine and their salts with bases. (I) are antibacterial agents with high activity against Gram-negative bacteria, e.g. with a curative ED50 of 8.6-9.8 mg/kg (p.o.) against infections by E.coli, Proteus mirabilis, Proteus vulgaris and Klebsiella Aeruginosa in mice. |
| priorityDate | 1978-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.