Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
filingDate |
1977-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ba0fc8fec39b978c7e2faa1b2496944 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ea0976faaa1fa860e073e6034c11e4e |
publicationDate |
1979-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-2748153-A1 |
titleOfInvention |
PROCESS FOR THE PRODUCTION OF 2-METHYL-4-AMINO-5-FORMYLAMINOMETHYLPYRIMIDINE |
abstract |
In the prodn. of 2-methy6-4-amino-5-(formamidomethyl) pyrimidine (I), a cpd. of formula (IV) (where each R is independently H, alkyl, aryl or aralkyl or N(R)2 is a heterocyclic ring) is reacted with acetamidine. Cpds. (IV) are new and are prepd. by reacting metal salts of 2-formyl-3-formamidopropionitrile (II) with salts of the amines HN(R)2 (III). (I) is an intermediate for vitamin B1. Simple process avoids the use of toxic dimethyl sulphate. (I) is obtained in good yield, and is suitable for direct use in vitamin B1 prodn. |
priorityDate |
1977-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |