| abstract |
Triphenylalkene derivatives of the general formula I <IMAGE> in which R is a C1-4-alkyl group and X is a halogen atom, where X has a meaning other than Cl if R is a methyl group, are obtained by dehydrogenation of a triphenyl alkanol derivative of the general formula II <IMAGE> in which R and X have the abovementioned meaning, while R1 and R2 have meanings which differ from one another and designate an H atom or an OH group. The resulting triphenylalkene derivatives inhibit to a considerable extent the growth of the hormone-dependent tumour induced by DMBA. |