http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2652821-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7f75780245ab029ad042060276ad22a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-50 |
| filingDate | 1976-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1469b9fe4ca144a62986109dcc28a77b |
| publicationDate | 1978-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2652821-A1 |
| titleOfInvention | THERAPEUTIC WITH BLOOD PRESSURE REDUCER AND / OR DIURETIC EFFECT AND PROCESS FOR MANUFACTURING THE ACTIVE SUBSTANCES |
| abstract | Therapeutic compsns. contain as active component an imidazoline of formula (I) or its acid addition salt. In (I) R' and R2 are each H, halogen, 1-4C alkyl, 1-4C alkoxy or CF3. Prepf. of (I) and their salts comprises reacting a phenyl isocyanidedihalide (II) with 2-aminoethylhydroazine (III) and opt. reacting with acid. (I) are known intermediates for therapeutically active substd. 2-phenylamino-imidazoline-2 cpds. (DT 2220906). They have now been discovered to have hypotensive and/or diuretic activity, and are useful for treating chronic hypertension. In an example, 1-amin-2-(2,6-dichlorophenylamino)-imidazoline-2- was prepd. from the corresp. dichloride and (III). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5258381-A |
| priorityDate | 1976-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.