http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2549410-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_856edac5eee772495ebdb2645385e9d5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-08 |
| filingDate | 1975-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a28c27027a16edc63cf8192d1e42b0e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c45a5c76cf25259c5bd60d03b21249 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_047125d4892c9e11b1450021de46d146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e429f10c9db46c9c185728c3e083064 |
| publicationDate | 1977-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2549410-A1 |
| titleOfInvention | 5-METHYL-ISOXAZOL-3-CARBOXYLATE, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PREPARATIONS CONTAINING THESE COMPOUNDS |
| abstract | New 5-metyl-isoxazole-3-carboxylates are salts of formula (I). In this formula R1 and R2 are H; 1-4C alkyl; hydroxyalkyl; alkoxyalkyl; or cycloalkyl. (I) have lipolysis-inhibiting and triglyceride-lowering activity. They can be used therapeutically for the treatment of hyperlipidaemias. Dosage as 1-10 mg one or more times per day. Details of biological tests showing the effects of (I; R1=Me, R2=CH2CH2OH) on lipid metabolism in rats are given in the specification. Thus, serum triglycerides are significantly lowered by doeses up to 5 mg/kg. The effect on serum cholesterol is only short-term: 300 mg/kg p.o. only lowers serum cholesterol for 3 hrs. after administration. Blood sugar levels are significantly lowered by does of 200 and 300 mg/kg. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0024122-A1 |
| priorityDate | 1975-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.