http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2528037-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-27 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 |
| filingDate | 1975-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfa6900557f963fc355992073d88c9d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4966cc62d4945930a7f9746e1da70bbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e45da4fa7ae4063dbde95b29170c7898 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_376b766a22585e34e1f5e161ad6d7fe4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_077598e70d3282c01defdee7e9f59887 |
| publicationDate | 1977-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2528037-A1 |
| titleOfInvention | PYRROLIDONE AND THE METHOD FOR MANUFACTURING THEIR |
| abstract | Pyrrolidone derivs. of formula (I) and their salts are new. In (1) A is -CH2CH2- or -C C-; B = -CH2CH2- or -CH=CH- but A and B are not both -CH2CH2-; R' = opt. branched alkyl or alkoxy; R2 = H, lower aliphatic hydrocarbon, or cycloaliphatic or araliphatic hydrocarbon of 3-8C; R3 = 1-10C alkyl(opt. substd. by 1-5C O- or S-alkyl), phenoxy (opt. substd. by 1-3C alkyl which may be substd. by halogen, or phenoxy opt. halogenated), O-furyl or O-benzyl (opt. substd. by 1-3C alkyl) and the side chains on the 3- and 4-positions of the pyrrolidone ring are trans to one another. (I) are luteolytics, gastric secretion inhibitors, broncho-spasmolytics and/or anti-hypertensives. Compared with natural prostaglandins they are more specific in action and longer acting. Typical compound is 1-methyl-3-(6-carbomethoxy-2-(I)hexynyl-)-4-(3-(RS)hydroxy-(E)-1- (I) hexenyl) pyrrolidone. The compounds are prepared by an 8-stage process starting from a 4-hydroxymethyl pyrrolidone. |
| priorityDate | 1975-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.