http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2509903-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00
filingDate 1975-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da1094b3c6ee93699df38710baeb300c
publicationDate 1976-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-2509903-A1
titleOfInvention N- (ALPHA, ALPHA-DIMETHYL-3,5-DIMETHOXYBENZYLOXYCARBONYL) -D-PHENYLGLYCINE AND COMPOUNDS DERIVED FROM IT AS INTERMEDIATES IN THE MANUFACTURE OF ANTIBIOTICS
abstract New cpds. of formulae (I), (IV) and (V), and their salts (R1 is H or OH; Ddz is alpha, alpha-dimethyl-3, 5-dimethoxybenzyl-oxycarbonyl; R2 is lower alkoxycarbonyl or lower aliphatic acyl; Cl is residue of 6-APA, 7-ACA or 7-ADCA, or their salts or esters, bonded via the 6/7 amino gp.). are intermediates in the synthesis of beta-lactam antibiotics having phenylglycyl or p-hydroxyphenylglycyl side chains, e.g. ampicillin, amoxycillin, cephalexin, pivampicillin and cephaloglycine. The 'Ddz' protecting gp. can be removed very quickly by photolysis or by acids, and permits the antibiotics to be prepd. in a single reaction vessel so improves yields and reduces process costs.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5158206-A
priorityDate 1975-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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