http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2509903-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
filingDate | 1975-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da1094b3c6ee93699df38710baeb300c |
publicationDate | 1976-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-2509903-A1 |
titleOfInvention | N- (ALPHA, ALPHA-DIMETHYL-3,5-DIMETHOXYBENZYLOXYCARBONYL) -D-PHENYLGLYCINE AND COMPOUNDS DERIVED FROM IT AS INTERMEDIATES IN THE MANUFACTURE OF ANTIBIOTICS |
abstract | New cpds. of formulae (I), (IV) and (V), and their salts (R1 is H or OH; Ddz is alpha, alpha-dimethyl-3, 5-dimethoxybenzyl-oxycarbonyl; R2 is lower alkoxycarbonyl or lower aliphatic acyl; Cl is residue of 6-APA, 7-ACA or 7-ADCA, or their salts or esters, bonded via the 6/7 amino gp.). are intermediates in the synthesis of beta-lactam antibiotics having phenylglycyl or p-hydroxyphenylglycyl side chains, e.g. ampicillin, amoxycillin, cephalexin, pivampicillin and cephaloglycine. The 'Ddz' protecting gp. can be removed very quickly by photolysis or by acids, and permits the antibiotics to be prepd. in a single reaction vessel so improves yields and reduces process costs. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5158206-A |
priorityDate | 1975-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.