http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2460335-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 |
| filingDate | 1974-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30764fcc4413674eb760c9814f597064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c5b11b58edaa49f59595bd1d115d586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1eb31eb87d5a6222585eba60a6ad32f1 |
| publicationDate | 1976-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2460335-A1 |
| titleOfInvention | PEPTIDES WITH LH-RH / FSH-RH EFFECT AND PROCESS FOR THEIR MANUFACTURING |
| abstract | Peptides of formula (I): (where X is Ser(But), Cys(But), Asp(OBut), Glu(OBut), Orn(Boc) or Lys(Boc); Y is glycinamide or NHR; R is 1-3C alkyl opt. substd. by OH or halogen, or cyclopropyl; and Trp can be replaced by pentamethylphenylalanine, Ser can be replaced by Ala or Thr. Tyr can be replaced by Phe, Gly can be replaced by a D-amino acid corresp. to a naturally occurring L-amino acid, Arg can be replaced by Orn, and Lys can be replaced by homoarginine), are analogues of the natural luteinising hormone/follicle stimulating hormone releasing hormone (LH-RH/FSH-RH) in which X=Leu and Y=Gly-NH2, and can thus be used for treating feminine and masculine sterility of hypophysical origin and in the diagnosis of hypophysis dysfunction; they are more than twice the activity of the natural LH-RH/FSH-RH and exhibit a pronounced depot effect. |
| priorityDate | 1974-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.