Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-28 |
filingDate |
1974-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6832676221c7190a3bfca99976b0242b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0accba40a9a1ca373c099e8b64a5648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daceb5b3b161865c56e36aa2bf3238b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_643c79a3e3dcf164971303e83c94e09f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ddc0f672791b01f6ad06decdd30d955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cd3e32e55cca519f488bd917149b3ee |
publicationDate |
1975-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
DE-2460039-A1 |
titleOfInvention |
PROCESS FOR THE PREPARATION OF HYDROXYMETHYLPYRIDINES |
abstract |
Hydroxymethyl-pyridines (e.g. 2,6-bis-hydroxymethyl-pyridine) are prepd by treating acetoxymethyl-pyridines with at least an equivalent amt of methanol (calculated on the basis of the number of acetyl gps) in the presence of base (pref. a volatile base, esp. NH3 or an org. tertiary base, or NaOH in anhydrous medium at a temp. between 0 degrees C and the b. pt of the reaction mixts the prod opt being isolated in the form of a salt. Hydroxymethylpyridines are useful as intermediates for pharmaceuticals, esp. cardiovascular agents (e.g. 2,6-dihydroxymethylpyridine bis(-N-methlcarbamate)). The process gives good yields and is suitable for large-scale use. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2835178-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6316664-B1 |
priorityDate |
1973-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |