http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2438619-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ad66884a6f2a66126d492e56e09be39 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08 |
| filingDate | 1974-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_804d40e94a4f9ffe889e5186e009f3de |
| publicationDate | 1976-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2438619-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-KETOPIPERAZINE DERIVATIVES |
| abstract | Substd. 2-ketopiperazine derivs. of general formula (I): (where R1 is aralkyl; R2 is H or 1-4C alkyl; R3 is H, OH, 1-4C alkoxy or benzyloxy and R4 and R5 each is H, 1-4C alkoxy or benzyloxy) are prepd. by (1) aralkylising aminoacid esters having general formula (II) (where R6 is 1-4C alkyl); (2) reacting in acid soln. with HCHO and HCN at low temps., and (3) catalytic reductive cyclisation of reaction prod. (I) are pref. converted to corresponding piperazine derivs. useful as therapeutic cpds. in treating heart conditions. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4483988-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0072932-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0072932-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0546868-A1 |
| priorityDate | 1974-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.