http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2430454-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1974-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f2a2912df9984c5ef72d84c4371ffa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_237ffea9f5eac9dd363fdb5215b743c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_772c890cc7d8eb31b9fc5ce115d06af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf66e2951590fff10844ac073aa4cb6 |
| publicationDate | 1976-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2430454-A1 |
| titleOfInvention | NEW PYRAZOLO SQUARE BRACKET ON 3.4D SQUARE BRACKET FOR PYRIMIDINE |
| abstract | amino)-pyrazolo/3,4-d/pyrimidine derivs. of formula (I): (where R1 is H, 1-3C alkyl, or phenyl opt. substd. by halogen or OCH; R3 is H, CH3, SCH3, benzylthio, methylsulphinyl or methylsulphonyl; and R4 and R6 are pierazino (ppt. substd. in the 4-posn. by acyl, carbamoyl, benzyl, 1-3C alkyl or 1-3C hydroxyalkyl), morpholino, thiamorpholino, 1-oxido-thiomorpholino 1,1-dioxido-thiomorpholino, hydrazino or alkenediamino, these residues opt. being C-substd. by 1 or 2 1-3C alkyl gps.), e.g. 4-(1-oxido-thiamorpholino)-6-piperazino-1H-pyrazolo/3,4-d/pyridim- idine, and their physiologically tolerable acid addition salts with inorganic or organic acids are new cpds. (I) have hypotensive and, esp. antithrombotic activity. (I) exhibit strong inhibition of thrombocyte aggregation and adhesiveness, this activity being accompanied by strong hypotensive activity when the cpds. carry a piperazino gp.; when the piperazino gp. is 4-substd. by acyl or lower alkyl, the cpds. have no influence on circulation and blood pressure. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H09505065-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021064077-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3800188-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6218397-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8343961-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9413677-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6200979-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005085248-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0691128-A1 |
| priorityDate | 1974-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.