| abstract |
Cpds. of formula (I) and their salts (where R1 = H, alkyl, alkoxy, opt. substd. phenyl or benzyl; R2 = H or alkyl; R3 = H, alkyl, opt. substd. phenyl, benzyl or phenethyl, R4 = alkyl, opt. substd. phenyl, cycloalkyl, heteroaryl or benzyl; R5 = H, alkyl,. opt. substd. phenyl or benzyl; R6 = alkyl; R7 = H or alkyl; X,Y,Z = a single bond or -CH2-; and R5 and R6 may be joined by a single bond) are useful as hypoglycemics which favourably influence the metabolism of fats and are used in the treatment of diabetes, hyperlipemia, adiposis etc. |