http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2357320-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f62898cdd573da928ee0f5ffa5f683 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-16 |
| filingDate | 1973-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0b62f63859e769ec25fc9bdbc32032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a3700a8fbb78f6980a8a153f2310fd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd07bc0266dfe03b16819862a3651a30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d0ad77319e697fc385e8f0dbdce4a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eb8837be129d6bd21f5886a356d0685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8581ebf80041f2c925fd077e3319e979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd8efbdecaa1dd14782dc077c6eae75b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e695be8c85f19948c515b8661e0f99ae |
| publicationDate | 1974-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2357320-A1 |
| titleOfInvention | TETRACYCLIC COMPOUNDS CONTAINING AN INDOLKIN IN THEIR STRUCTURE, THEIR SALTS AND METHOD FOR THEIR PRODUCTION |
| abstract | Compounds of formula (I) and acid addition salts thereof are new: (R=H, alkyl or alkoxy; R'= alkyl; m and n are 2 or 3; pref. alkyl have 1-4C). Some unspecified starting materials of formula (II) (see 'Preparation') are also new. (I) are antidepressants. They potentiate the effects of phenamine or 5-hydroxytryptophan on the CNS and of adrenaline, serotonin, tryptamine etc. on the peripheral nervous system, but do not potentiate hexenal, promethol or novacaine. Their activity does not depend on monoamino-oxidase inhibition. 1-Oxo-10-(2-dimethylaminoethyl)-1H,2,3,4,5-tetrahydroazepino 3,4-- b indole (2 g) and POCl3 (10 ml) were refluxed 4 hrs., evapd. in vacuo, residue cooled and appropriate (III) recovered. This was treated with aq. ammonia, extracted with benzene, dried and evapd. to give 50% yield of (I, m=2, n=3, R=H, R'= methyl)m.pt. 138-9 degrees C (hexane). |
| priorityDate | 1972-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.