http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2315884-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15fdc396b5ab19e14231994f07fa0114 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 |
| filingDate | 1973-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_810b182eff28a3a1466720601362d053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_297f081a4857cf67d1fee79bdb1aede0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6820abf93956104820bdf17340c9d88d |
| publicationDate | 1974-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2315884-A1 |
| titleOfInvention | PROCESS FOR THE PRODUCTION OF DESOXYRIBONUCLEOSIDES |
| abstract | Desoxyribonucleosides (I) are prepd. from ribonucleosides (II) by (a) converting (II) into a nucleoside-5'-carboxylic acid or alkyl, aryl or aralkyl ester thereof, (b) reacting this with an esterifying agent (esp. tosyl chloride) in at least the stoichiometric amt. in a polar solvent (e.g. pyridine) at 0 degrees C (pref. -10 to -30 degrees C) for >=10 hrs. (pref. 5-20 days), (c) isolating and purifying the resulting 2'-esterified cpd. (d) reducing this with NaBH4, and (e) converting the resulting 2'-esterified hydroxymethyl nucleoside deriv. to the corresp. desoxynucleoside in known manner. Very little diester is formed in (b), thus increasing the yield to >=10% compared with the normal 2-3%. |
| priorityDate | 1973-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.