| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 |
| filingDate |
1972-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aa958684f2df31882c6bd761c7a70bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24f17fd67e59ce02396c55fee5f1647c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_553ac6b00cb9231df91533ee06131ef6 |
| publicationDate |
1974-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
DE-2258088-A1 |
| titleOfInvention |
OPTICALLY ACTIVE ISOINDOLINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
| abstract |
Optically active, dextrorotatory isoindoline derivs of formula (I) (where R is 1-4C alkyl and R1 is H 1-4C alkyl, or a group -(CH2)n-NR2R3 in which n is 1 or 2 and R2 and R3 are H or 1-4C alkyl) and their salts with optically active or inactive bases have analgesic and anti-inflammatory activity which is stronger than that of the corresponding racemic compounds. (I) are produced by converting the racemic cpd. corresponding to (I; R1 = H) into a salt with an optically active base, separating the diastereomeric salts obtd. opt. releasing the free cpd. (+)-(I; R1=H) from the corresponding salt, and opt. esterifying (+)-(I; R1=H) thus obtd. cpd. in a conventional manner. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2204579-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009530306-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2612185-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2204579-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GR-880100137-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BE-1003280-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-392068-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0759555-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63238058-A |
| priorityDate |
1970-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |