| abstract |
Substn. is on the C atom alpha-to the amine N, using a nitrosamine of a sec. amine having >=1 H atom alpha to the amine N. Process is used for chemical synthetics (e.g., by reducing prods. to assymetrically substd. hydrazines or denitrosylation to amino cpds.) and for studying biochemical processes, esp., in cancer research. Metallisation is e.g., with alkali(ne earth) metal, Zn, Cd or Cu, and electrophilic is pref. a carbonyl cpd. |