http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2212371-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-60 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
filingDate | 1972-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7fb6f2528bfad2f477986651f821aab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e80f087b681d43da556bba5c7ad9b65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a8488be70a51e3dc6f49a12e469cbab |
publicationDate | 1973-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | DE-2212371-A1 |
titleOfInvention | NEW 2-METHYLENE-3-SPIROCYCLOALKAN2,3-DIHYDRO-5-OXO-5-H-THIAZOLO-SQUARE CLIP ON 2.3-SQUARE BRACKET ZUCHINAZOLINE AND THEIR PRODUCTION |
abstract | Thiazoloquinazoline derivs. of formula (I): (where n is 4, 5, 6 or 7; and R' and R2 are H, halogen, lower alkyl, OH, alkoxy, NO2, NH2 or SO3H). Bactericides and fungicides. Also anti-inflammatories, analgesics and sedatives. EXAMPLE A mixture of o-isothiocyanatobenzoic acid methyl ester (5.8 g), 1-ethynyl-cyclohexylamine (3.7 g) and n-PrOH (50 ml) is stirred 1 hr. at room temp., refluxed 2 hrs., cooled, treated with KOH (0.3 g) in H2O (1 ml), refluxed 2 hrs., and evapd. The residue is taken up in CH2Cl2 and the soln. is washed with dilute HCl and water, dried (Na2SO4) and evapd. The residue (8.5 g) is recrystallized from EtOH (charcoal) to give 2-methylene-3-spirocyclohexan-2,3-dihydro-5-oxo-5H-thiazolo- 2,3-- b quinazoline (6.4 g), m.pt. 119-120 degrees. |
priorityDate | 1972-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.