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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04
filingDate 1972-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7fb6f2528bfad2f477986651f821aab
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publicationDate 1973-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-2212371-A1
titleOfInvention NEW 2-METHYLENE-3-SPIROCYCLOALKAN2,3-DIHYDRO-5-OXO-5-H-THIAZOLO-SQUARE CLIP ON 2.3-SQUARE BRACKET ZUCHINAZOLINE AND THEIR PRODUCTION
abstract Thiazoloquinazoline derivs. of formula (I): (where n is 4, 5, 6 or 7; and R' and R2 are H, halogen, lower alkyl, OH, alkoxy, NO2, NH2 or SO3H). Bactericides and fungicides. Also anti-inflammatories, analgesics and sedatives. EXAMPLE A mixture of o-isothiocyanatobenzoic acid methyl ester (5.8 g), 1-ethynyl-cyclohexylamine (3.7 g) and n-PrOH (50 ml) is stirred 1 hr. at room temp., refluxed 2 hrs., cooled, treated with KOH (0.3 g) in H2O (1 ml), refluxed 2 hrs., and evapd. The residue is taken up in CH2Cl2 and the soln. is washed with dilute HCl and water, dried (Na2SO4) and evapd. The residue (8.5 g) is recrystallized from EtOH (charcoal) to give 2-methylene-3-spirocyclohexan-2,3-dihydro-5-oxo-5H-thiazolo- 2,3-- b quinazoline (6.4 g), m.pt. 119-120 degrees.
priorityDate 1972-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 36.