http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2209019-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 |
| filingDate | 1972-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd4863db1c923aa5e9e8ceb4711b986 |
| publicationDate | 1973-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2209019-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF 3-THIOMETHYLCEPHALOSPORINE COMPOUNDS |
| abstract | In a process for the prodn. of (I) (where X is Cl, Br or I; R is 1-6C alkyl, Z-CH- or Z-(CH2)m-A-(CH2)n-; Z is thineyl, furyl or Y is protected amino or hydroxy; Ais O, S or a bons; m is 0-4; n is 1-4; Q is H, F, Cl, Br, 1-6C alkyl, MeO, EtO, NO2 CN, OH or CF3; R1 is H, 1-6C alkyl, 1-6C haloalkyl, 3-8C alkenyl, 3-8C alkynyl, benzyl, methoxy benzyl, nitrobenzyl, Ph2CH, Ph3C, phthalimidomethyl, succinimidomethyl phenacyl or Me3Si, R2 is 1-6C alkyl, 2-6C alkyl (opt. substd. by OH, NO2, Di-(1-4C) alkylamino, CN or halo) 3-6C alkenyl, PhCH2, Ph pyridyl. thienyl,furyl, thiadiazyl, tetrazyl or CH2COR3; R3 is OR4 or N(R4)2, R4 is H or 1-4C alkyl and p is 0 or 1) the corresponding 3-halomethyl deriv. is reacted with R2SH at 0-50 degrees in the presence of DMF, DMA or HMPA. Thus (I, R = PhOCH2, R1 = p-nitrobenzyl and R2 = Me) is prepd. from the 3-bromomethyl deriv. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5686188-A |
| priorityDate | 1972-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.