http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2137341-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 1971-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f2a2912df9984c5ef72d84c4371ffa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_237ffea9f5eac9dd363fdb5215b743c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_772c890cc7d8eb31b9fc5ce115d06af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf66e2951590fff10844ac073aa4cb6 |
| publicationDate | 1973-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2137341-A1 |
| titleOfInvention | NEW THIENO SQUARE BRACKET ON 3.2 SQUARE BRACKET FOR PYRIMIDINE |
| abstract | New cpds. of formula (I) (where R1 and R2 are piperazino (opt. 4-substd. by PhCH2, lower alkyl and/or hydroxyalkyl) 1,4-diazacycloheptano morpholino, thiomorpholino, (or its 1-oxide or 1,1-dioxide) hexahydro-1,4-thiazepino (or its 1-oxide) (all these heterocycles are opt. substd. by 1 or 2 lower alkyl gps) dialkanolamino, methylthioethyl-methylamino and/or methylsulphinylethyl-methylamino; R3 and R4 are H, halogen, lower alkyl, Ph and/or NO2) and their acid addn. salts are prepd. in a manner known for analogous cpds. pref. by reacting the corresp. cpd. with an exchangeable gp. e.g. halogen, SH or an alkyl, aryl or aralkyl-thio, -sulphinyl or sulphonyl, in posn. 2 or 4 with R1H or R2H at 0-250 degrees C. (I) where R1 and/or R2 are opt. alkyl-substd. thiomorpholino, hexahydro-1,4-thiazepino or methyl-thioethyl-methylamino can be converted into the corresp. S-oxides or S,S-dioxides by oxidn. Cpds. (I) inhibit thrombocyte aggregation and adhesion, and some have hypotensive activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10561658-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1544202-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1544202-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10646490-B2 |
| priorityDate | 1971-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.