http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2119977-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20 |
| filingDate | 1971-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1971-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2119977-A1 |
| titleOfInvention | Antiphlogistic and antisecretory napththisoxazoles - from 1-hydroxyim - 2-carbonyl derivs by intramolecular condensation |
| abstract | Naphthisoxazoles (I): (where ring A can opt. carry a substituents; ring B can opt. have a C=C bond in 4-posn. and R is CH3, CH2OH, CH2Oalk, aminoalkoxymethyl, CH2hal, CH2NH2, CN or -C(=Y)-R1 where R1 is OH, is not >12C hydrocarbon gp., oxy, opt. substd. NH2 or a gp. OM1/n where M is alkali or alk. earth metal, Al, NH4 or an org. base, and n is valency of metal M, and Y is O or S provided that Y=O if R1=OH or Oalk or OM1/n). Prefd. cpds. are naphth- 1,2-c isoxazole-3-carboxylic acid, its 4,5-dihydroanalogue and the C1-3 alkyl esters of the latter. Prepn. by intramolecular condensation of 1-hydroxyiminonaptho-2-carbonyl derivs. in presence of dehydrating agts. In an example, 18 g. methyl-4,5-dihydronaphthisoxazole-3-carboxylate, m.pt. 146 degrees are obtained by saturating and refluxing a soln. of 20 g. methyl-1-hydroxyimino-1,2,3,4-tetrahydronaphtho-2-glyoxalate in MeOH with dry HCl-gas for 1 1/2 hrs. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5670522-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9725317-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5880121-A |
| priorityDate | 1971-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 478.