http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2043614-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00 |
| filingDate | 1970-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1971-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | DE-2043614-A1 |
| titleOfInvention | Hydroxy benzodiazepine derivs with sedative - activity |
| abstract | 3-Hydroxy-1,4-benzodiazepine derivs. with sedative, muscle-relaxant and anticonvulsive properties, have formula (I) or consist of salts thereof (where R1 is H or (hydroxy)alkyl; R2 and R3 are H, halogen, alkyl(thio), alkoxy, CF3 or CN). (I) are prepared by (i) cyclising a benzophenone-alpha-oxime X is halogen in an inert organic solvent in presence of a proton acceptor, with heating and (ii) isomerising the 1,4-benzodizepine-4-oxides (III) obtained with Lewis acids, such as AlCl3 or BF3, in presence of a nitrile; (iii) separating (I) produced and optionally converting to non-toxic salts, and optionally separating intermediate addition cpds. (IV) Y is Lewis acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2194432-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2338058-A1 |
| priorityDate | 1969-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.