http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2040643-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-367
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-367
filingDate 1970-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8e48b20a68d6af5c9422225a19d9f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dba2520b0a840fb8444308daa7a1ee6
publicationDate 1972-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber DE-2040643-A1
titleOfInvention Process for the production of hydroxyphenyl acetic acids
abstract Cpds. of general formula (I) : (where n is 1,2 or 3) are prepd. by reacting halophenyl acetic acids of formula (II): (where Hal is F, Cl or Br) with alkalihydroxides at 150-300 degrees C under pressure and in the presence of a combination of copper salts and metallic copper or Cu-cps. produced from the combination during reaction. The acids are then liberated from the salts obtained. (1) are intermediates in the synthesis of choleretically-active cpds. The process gives high yields of high purity. The metallic Cu may be in the form of powder, shavings or the wall of the copper reaction vessel.
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