| abstract |
A transdermal patch for administering fentanyl or an analog thereof through the skin, comprising: (a) a backing sheet, and (b) a reservoir disposed on the carrier sheet, the supply comprising a monophase polymer composition of a polyacrylate adhesive, free of undissolved constituents, having a content of fentanyl or an analog thereof sufficient to induce analgesia in humans and at least three Upkeep days, wherein the polyacrylate adhesive is crosslinked and has a solubility for fentanyl or its analogues of between 1% to 25% by weight. |